International activities

Overview | Funding | Publications | International activities | Community | Summary

My research investigates approaches for deriving and validating prediction models when multiple sources of evidence are available. Particularly, we propose methods to aggregate previously published prediction models and associations with new data, methods to combine multiple datasets, methods to quantify heterogeneity and interpret external validity.

 

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2017

Vigo, Spain. 38th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Statistical methods for systematic reviews. Meta-analysis of external validation studies. Oral Presentation. 10th Jul 2017.

Utrecht, The Netherlands. Utrecht Bioinformatics Center. UBC seminar. Developing and validating prediction models using large clustered datasets and meta-analysis. Oral Presentation. 12th Jun 2017.

Keele, United Kingdom. Research Institute for Primary Care and Health Sciences, Keele University. Statistical Methods for Evidence Synthesis of Individual Participant Data. Multiple Imputation in Individual Participant Data Meta-Analysis. Invited speaker. 8th Jun 2017.

London, United Kingdom. Blizard Institute. Barts and The London School of Medicine and Dentistry. Queen Mary University of London. Individual Patient Data Symposium. Use of multiple IPDs in developing prediction models. Invited speaker. 28th Apr 2017.

Brussels, Belgium. European Organisation for Research and Treatment of Cancer (EORTC). statclub. A gentle introduction into network meta-analysis. Invited speaker. 28th Mar 2017.

Amsterdam, Netherlands. ECCO2017: European Cancer Congress. Changing Practice Session: External Validity of Clinical Trials. Modelling effectiveness from clinical trials. Invited speaker. 30th Jan 2017.

2016

Keele, United Kingdom. Research Institute for Primary Care and Health Sciences, Keele University. Statistical Methods for Evidence Synthesis of Individual Participant Data. Multiple Imputation in Individual Participant Data Meta-Analysis. Invited speaker. 7th Dec 2016.

Leuven, Belgium. Department of Electrical Engineering (ESAT), University of Leuven. Clinical Risk Prediction Models Based On Multicenter Data. Predicting the unknown in health care: challenges and opportunities. Invited speaker. 1st Dec 2016.

Brussels, Belgium. European Federation of Statisticians in the Pharmaceutical Industry (EFSPI). European Statistical Meeting on Evidence Synthesis. Network Meta-Analysis using Individual Participant Data. Invited speaker. 22nd Nov 2016.

Seoul, South Korea. Cochrane. 24th Cochrane Colloquium. Systematic reviews of prognostic studies 3: meta-analytical approaches in systematic reviews of prognostic studies. Workshop. 27th Oct 2016.

Seoul, South Korea. Cochrane. 24th Cochrane Colloquium. Network meta-analysis using individual participant data: when do benefits arise?. Oral Presentation. 27th Oct 2016.

Seoul, South Korea. Cochrane. 24th Cochrane Colloquium. Dealing with missing data in an individual participant data meta-analysis: one-stage versus two-stage methods. Oral Presentation. 27th Oct 2016.

Seoul, South Korea. Cochrane. 24th Cochrane Colloquium. Individual participant data (IPD) meta-analysis of prognostic studies: combining aggregate data and IPD. Workshop. 25th Oct 2016.

Seoul, South Korea. Cochrane. 24th Cochrane Colloquium. Individual participant data (IPD) meta-analysis of prognostic studies. Workshop. 24th Oct 2016.

Seoul, South Korea. Cochrane. 24th Cochrane Colloquium. Systematic review and meta-analysis of external validation studies of multivariable diagnostic or prognostic models: a primer. Oral Presentation. 24th Oct 2016.

London, United Kingdom. IMI GetReal. Evidence Synthesis and Predictive Modelling of Relative Effectiveness: paving the way to best practice. Network Meta-Analysis including Individual Participant Data. Invited speaker. 15th Sep 2016.

Birmingham, United Kingdom. 37th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Missing data. Dealing with missing data in an Individual Participant Data Meta-Analysis. Poster Presentation. 23rd Aug 2016.

Birmingham, United Kingdom. 37th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Meta-analysis in medical decision making. An overview of methods for network meta-analysis using individual participant data: when do benefits arise?. Poster Presentation. 22nd Aug 2016.

London, United Kingdom. Royal Statistical Society. Methods in Meta-analysis. Systematic review and meta-analysis of external validation studies. Oral Presentation. 4th Jul 2016.

Berlin, Germany. Promoting Statistical Insight (PSI). 2016 PSI Conference. Bridging efficacy to effectiveness: The IMI GetReal project. Invited speaker. 23rd May 2016.

Keele, United Kingdom. Research Institute for Primary Care and Health Sciences, Keele University. Statistical Methods for Evidence Synthesis of Individual Participant Data. Multiple Imputation in Individual Participant Data Meta-Analysis. Invited speaker. 17th May 2016.

Goettingen, Germany. Institut für Medizinische Statistik, University of Goettingen. Individual Participant Data (IPD) Meta-analysis of prediction modelling studies. Invited speaker. 7th Mar 2016.

Manchester, United Kingdom. IMI GetReal. GetReal Annual Meeting. Individual Participant Data Network Meta-Analysis (IPD-MA). Invited speaker. 10th Feb 2016.

Manchester, United Kingdom. IMI GetReal. GetReal Annual Meeting. Review of best practices in evidence synthesis and predictive modelling of relative effectiveness. Invited speaker. 10th Feb 2016.

2015

Keele, United Kingdom. Research Institute for Primary Care and Health Sciences, Keele University. Statistical Methods for Evidence Synthesis of Individual Participant Data. Multiple Imputation in Individual Participant Data Meta-Analysis. Invited speaker. 3rd Dec 2015.

Milan, Italy. Amgen. IMI GetReal Work Package 4 methods workshop. IPD network meta-analysis. Invited speaker. 12th Nov 2015.

London, United Kindgom. International Prediction of Pre-eclampsia IPD Collaborative Network (IPPIC). IPD meta-analysis consensus meeting. IPD meta-analysis in prognostic research. Invited speaker. 6th Nov 2015.

Boston, United States. Biogen. Worldwide Medical Biostatistics Multiple Sclerosis Advisory Board Meeting. Development and Validation of Clinical Prediction Models using Multiple Individual Participant Data (IPD) Sets: Distinguishing between Reproducibility, Transportability, and Generalizability. Invited speaker. 24th Oct 2015.

Vienna, Austria. Cochrane. 23rd Cochrane Colloquium. Individual Participant Data (IPD) meta-analysis of prognostic studies. Workshop. 7th Oct 2015.

Vienna, Austria. Cochrane. 23rd Cochrane Colloquium. Individual Participant Data (IPD) meta-analysis of diagnostic and prognostic modeling studies: a practical introduction to their rationale and conduct. Oral Presentation. 7th Oct 2015.

Vienna, Austria. Cochrane. 23rd Cochrane Colloquium. Systematic reviews of prognostic studies 4: quantitative synthesis and meta-analytical approaches. Workshop. 6th Oct 2015.

Vienna, Austria. Cochrane. 23rd Cochrane Colloquium. Statistical models for network meta-analysis: an empirical comparison. Oral Presentation. 5th Oct 2015.

Vienna, Austria. Cochrane. 23rd Cochrane Colloquium. Methods for individual participant data meta-analysis of relative treatment effects: a methodologic overview. Poster Presentation. 5th Oct 2015.

Vienna, Austria. Cochrane. 23rd Cochrane Colloquium. Imputation of systematically missing predictors in an individual participant data meta-analysis: a generalized approach using MICE. Oral Presentation. 4th Oct 2015.

Utrecht, Netherlands. 36th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Subgroup analysis. Methods for Individual Participant Data meta-analysis of relative treatment effects: a methodological overview. Oral Presentation. 27th Aug 2015.

Utrecht, Netherlands. 36th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Meta-analysis. Statistical models for network meta-analysis: an empirical comparison. Oral Presentation. 25th Aug 2015.

London, United Kingdom. Royal Statistical Society. Methods in Meta-analysis. An evaluation of statistical methods for Individual Participant Data Network Meta-Analysis. Oral Presentation. 21st Jul 2015.

2014

Bern, Switzerland. Institut für sozial- und präventivmedizin, University of Bern. Methods for IPD meta-analysis: a systematic review. Invited speaker. 1st Dec 2014.

Hyderabad, India. Cochrane. 22nd Cochrane Colloquium. Systematic reviews of prognostic studies: a meta-analytical approach. Workshop. 26th Sep 2014.

Hyderabad, India. Cochrane. 22nd Cochrane Colloquium. Publication bias tests for survival data: a simulation study. Oral Presentation. 25th Sep 2014.

Hyderabad, India. Cochrane. 22nd Cochrane Colloquium. Multiple imputation of systematically missing predictors in an individual participant data meta-analysis: a generalized approach using MICE. Oral Presentation. 24th Sep 2014.

Hyderabad, India. Cochrane. 22nd Cochrane Colloquium. How to appraise Individual Participant Data (IPD) meta-analysis in diagnostic and prognostic risk prediction research. Poster Presentation. 24th Sep 2014.

Hyderabad, India. Cochrane. 22nd Cochrane Colloquium. Individual participant data (IPD) meta-analysis of risk prediction studies. Workshop. 23rd Sep 2014.

Hyderabad, India. Cochrane. 22nd Cochrane Colloquium. Systematic reviews of prediction modelling studies: designing, critical appraisal and data collection. Workshop. 23rd Sep 2014.

Vienna, Austria. 35th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Individual participant data meta-analysis. Multiple imputation of systematically missing predictors in an individual participant data meta-analysis: a generalized approach using MICE. Oral Presentation. 26th Aug 2014.

Vienna, Austria. 35th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Individual participant data meta-analysis. How to appraise Individual Participant Data (IPD) meta-analysis in diagnostic and prognostic risk prediction research. Oral Presentation. 26th Aug 2014.

Vienna, Austria. 35th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Meta-analysis and network meta-analysis. Publication bias tests for survival data: a simulation study. Poster Presentation. 26th Aug 2014.

London, United Kingdom. Royal Statistical Society. Methods in Meta-analysis. Publication bias tests for survival data: a simulation study. Oral Presentation. 6th Jun 2014.

Nijmegen, Netherlands. Department for Health Evidence & Nijmegen Centre for Evidence Based Practice, Radboud University Medical Center. Health Evidence Seminar. Meta-analysis of clinical prediction models. Invited speaker. 13th May 2014.

Zeist, Netherlands. IMI GetReal. IMI GetReal Kick-off Meeting. Review of methods for IPD meta-analysis. Invited speaker. 29th Jan 2014.

2013

Quebec, Canada. Cochrane. 21th Cochrane Colloquium. A framework for individual participant data meta-analysis in the presence of missing data. Oral Presentation. 22nd Sep 2013.

Quebec, Canada. Cochrane. 21th Cochrane Colloquium. A framework to interpret external validation studies of prediction models. Oral Presentation. 22nd Sep 2013.

Quebec, Canada. Cochrane. 21th Cochrane Colloquium. Individual participant data meta-analysis for a binary outcome: one-stage or two-stage?. Oral Presentation. 21st Sep 2013.

Munich, Germany. 34th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Causal inference and meta-analysis. Meta-analysis and aggregation of multiple published prediction models. Oral Presentation. 26th Aug 2013.

Munich, Germany. 34th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Poster Exhibition. A framework to interpret external validition studies of prediction models. Poster Presentation. 26th Aug 2013.

Munich, Germany. 34th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Poster Exhibition. A framework for individual participant data meta-analysis in the presence of missing data. Poster Presentation. 26th Aug 2013.

Birmingham, United Kingdom. College of Medical and Dental Sciences, University of Birmingham. Methods for Evaluating Medical Tests and Biomarkers Symposium 2013. Meta-analysis and aggregation of multiple published prediction models. Poster Presentation. 16th Jul 2013.

Birmingham, United Kingdom. College of Medical and Dental Sciences, University of Birmingham. Methods for Evaluating Medical Tests and Biomarkers Symposium 2013. A framework for developing, implementing and evaluating clinical prediction models in an individual participant data meta-analysis. Oral Presentation. 16th Jul 2013.

London, United Kingdom. Royal Statistical Society. Methods in Meta-analysis. Individual Participant Data Meta-Analysis with systematically missing predictors. Oral Presentation. 9th Jul 2013.

Utrecht, Netherlands. Vereniging voor Epidemiologie (VvE). The annual epidemiology conference WEON 2013. A framework to interpret external validation of clinical prediction models and their generalizability. Oral Presentation. 7th Jun 2013.

Utrecht, Netherlands. Vereniging voor Epidemiologie (VvE). The annual epidemiology conference WEON 2013. Meta-analysis and aggregation of multiple published prediction models. Poster Presentation. 7th Jun 2013.

Utrecht, Netherlands. Faculty of Social and Behavioural Sciences, Utrecht University. Seminar on Missing Data. A framework for Individual Participant Data Meta-Analysis in the presence of missing data. Oral Presentation. 14th Jan 2013.

2012

London, United Kingdom. Royal Statistical Society. Methods in Meta-analysis. Aggregating published prediction models with individual participant data. Oral Presentation. 14th Dec 2012.

Utrecht, Netherlands. Julius Center for Health Sciences and Primary Care, Utrecht University. Julius Seminar. A framework for developing, implementing and evaluating clinical prediction models in an IPD meta-analysis. Oral Presentation. 22nd Nov 2012.

Auckland, New Zealand. Cochrane. 20th Cochrane Colloquium. A framework for developing and implementing clinical prediction models across multiple studies. Oral Presentation. 3rd Oct 2012.

Auckland, New Zealand. Cochrane. 20th Cochrane Colloquium. Aggregating published prediction models with individual participant data: combining models with different predictors. Oral Presentation. 3rd Oct 2012.

Auckland, New Zealand. Cochrane. 20th Cochrane Colloquium. A framework for evaluating and distinguishing validity and generalization of prediction models. Poster Presentation. 1st Oct 2012.

Bergen, Norway. 33th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Prediction. A framework for developing and implementing clinical prediction models across multiple studies with binary outcomes. Oral Presentation. 22nd Aug 2012.

Bergen, Norway. 33th Annual Conference of the International Society for Clinical Biostatistics (ISCB). Prediction. Aggregating published prediction models with individual patient data. Poster Presentation. 21st Aug 2012.

Utrecht, Netherlands. Julius Center for Health Sciences and Primary Care, Utrecht University. Studio Biostatistics. A framework for developing, implementing and evaluating clinical prediction models across multiple studies with binary outcomes. Oral Presentation. 26th Jun 2012.

Rotterdam, Netherlands. Vereniging voor Epidemiologie (VvE). The annual epidemiology conference WEON 2012. A framework for evaluating and distinguishing validity and generalization of prediction models. Poster Presentation. 15th Jun 2012.

Rotterdam, Netherlands. Vereniging voor Epidemiologie (VvE). The annual epidemiology conference WEON 2012. A framework for developing, implementing and evaluating clinical prediction models across multiple studies with binary outcomes. Oral Presentation. 15th Jun 2012.

Rotterdam, Netherlands. Vereniging voor Epidemiologie (VvE). The annual epidemiology conference WEON 2012. Aggregating published prediction models with individual participant data: combining models with different predictors. Oral Presentation. 15th Jun 2012.

Birmingham, United Kingdom. School of Mathematics, University of Birmingham. Statistics Seminar. Clinical Prediction Modeling and External Knowledge. Invited speaker. 13th Jan 2012.

2011

London, United Kingdom. Royal Statistical Society. Methods in Meta-analysis. Incorporating published univariable associations in diagnostic and prognostic modeling. Oral Presentation. 12th Dec 2011.

Birmingham, United Kingdom. Department of Public Health and Biostatistics, University of Birmingham. Book Club. Case study on Dealing with Missing Values. Invited speaker. 5th Dec 2011.

Birmingham, United Kingdom. Department of Public Health and Biostatistics, University of Birmingham. Seminar. Regression modelling with prior evidence. Invited speaker. 30th Nov 2011.

Madrid, Spain. Cochrane. 19th Cochrane Colloquium. Aggregating published prediction models with individual patient data: a comparison of different approaches. Poster Presentation. 22nd Oct 2011.

Madrid, Spain. Cochrane. 19th Cochrane Colloquium. Meta-analytical approaches for diagnostic and prognostic prediction research: incorporating published univariable associations in multivariable analysis of individual patient data. Poster Presentation. 22nd Oct 2011.

Utrecht, Netherlands. Julius Center for Health Sciences and Primary Care, Utrecht University. Workshop: Diagnostic test evaluation in the absence of a (gold) reference standard. Multivariate Meta-Analysis: A Comparison of Approaches. Invited speaker. 12th Sep 2011.

Ottawa, Canada. 32nd Annual Conference of the International Society for Clinical Biostatistics (ISCB). Prediction models. Aggregating Published Prediction Models with Individual Patient Data: A Comparison of Approaches. Oral Presentation. 24th Aug 2011.

IJmuiden, Netherlands. Vereniging voor Epidemiologie (VvE). The annual epidemiology conference WEON 2011. Aggregating published prediction models with individual patient data: Approaches to improve predictions across patient populations. Oral Presentation. 10th Jun 2011.

2010

Montpellier, France. 31st Annual Conference of the International Society for Clinical Biostatistics (ISCB). Meta-analyses. Meta-analysis of clinical prediction models: Incorporating published univariable associations in the analysis of individual patient data. Poster Presentation. 29th Aug 2010.

Nijmegen, Netherlands. Vereniging voor Epidemiologie (VvE). The annual epidemiology conference WEON 2010. Meta-analysis of clinical prediction rules: incorporating known univariate associations as prior knowledge when analyzing multivariate data. Oral Presentation. 10th Jun 2010.